Application
Western blot analysis of CPZ Antibody (N-term) (Cat.# AP6546a) in K562 cell line lysates (35ug/lane). CPZ (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | CPZ Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPZ; Carboxypeptidase Z |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CPZ Carboxypeptidase Z |
|---|---|
| Molecular Weight(MW) | 73655 Da |
| Function | Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing |
| Tissue Specificity | In placenta, it is present within invasive trophoblasts and in the surrounding extracellular space. Also present in amnion cells, but is not readily apparent in the extracellular matrix of this cell type. Present in normal pituitary gland and neoplastic pituitary gland (especially POMC-, GH- and PRL-producing adenomas) (at protein level). Widely expressed |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 8532 |
|---|
Application
Western blot analysis of CPZ Antibody (N-term) (Cat.# AP6546a) in K562 cell line lysates (35ug/lane). CPZ (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human placenta with CPZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
