Application
Western blot analysis of CQ068 Antibody (Center) in K562 cell line lysates (35ug/lane). CQ068 (arrow) was detected using the purified Pab.Application
CQ068 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CQ068 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTC1; C17orf68; CST complex subunit CTC1; Conserved telomere maintenance component 1; HBV DNAPTP1-transactivated protein B |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C17orf68 |
|---|---|
| Alternative Names | CTC1 C17orf68 CST complex subunit CTC1 Conserved telomere maintenance component 1 HBV DNAPTP1-transactivated protein B |
| Molecular Weight(MW) | 134609 Da |
| Function | Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites |
| Tissue Specificity | This CQ068 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774~803 amino acids from the Central region of human CQ068. |
| Cellular Localization | Nucleus. Chromosome, telomere. Note=A transmembrane region is predicted by sequence analysis tools (ESKW, MEMSAT and Phobius); however, given the telomeric localization of the protein, the relevance of the transmembrane region is unsure in vivo |
| Entrez Gene | 80169 |
|---|
Application
Western blot analysis of CQ068 Antibody (Center) in K562 cell line lysates (35ug/lane). CQ068 (arrow) was detected using the purified Pab.
Application
CQ068 Antibody (Center) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
