Application
CRB3 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the CRB3 antibody detected the CRB3 protein (arrow).| Product Name | CRB3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRB3; Crumbs protein homolog 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CRB3 Crumbs protein homolog 3 |
|---|---|
| Molecular Weight(MW) | 12854 Da |
| Function | Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions |
| Tissue Specificity | Preferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate |
| Cellular Localization | Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells |
| Entrez Gene | 92359 |
|---|---|
| Nucleotide Accession | NP_631900.1 NP_777377.1 |
Application
CRB3 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the CRB3 antibody detected the CRB3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
