Application
Western blot analysis of CREB3L2 Antibody (C-term) in Hela cell line lysates (35ug/lane). CREB3L2 (arrow) was detected using the purified Pab.| Product Name | CREB3L2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CREB3L2; BBF2H7; Cyclic AMP-responsive element-binding protein 3-like protein 2; BBF2 human homolog on chromosome 7; Processed cyclic AMP-responsive element-binding protein 3-like protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BBF2H7 |
|---|---|
| Alternative Names | CREB3L2 BBF2H7 Cyclic AMP-responsive element-binding protein 3-like protein 2 BBF2 human homolog on chromosome 7 Processed cyclic AMP-responsive element-binding protein 3-like protein 2 |
| Molecular Weight(MW) | 57415 Da |
| Function | Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage (By similarity) |
| Tissue Specificity | Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type II membrane protein |
| Entrez Gene | 64764 |
|---|
Application
Western blot analysis of CREB3L2 Antibody (C-term) in Hela cell line lysates (35ug/lane). CREB3L2 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
