MED27; CRSP34; CRSP8; Mediator of RNA polymerase II transcription subunit 27; Cofactor required for Sp1 transcriptional activation subunit 8; Mediator complex subunit 27; P37 TRAP/SMCC/PC2 subunit; Transcriptional coactivator CRSP34
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:50~100
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CRSP34 CRSP8
Alternative Names
MED27 CRSP34 CRSP8 Mediator of RNA polymerase II transcription subunit 27 Cofactor required for Sp1 transcriptional activation subunit 8 Mediator complex subunit 27 P37 TRAP/SMCC/PC2 subunit Transcriptional coactivator CRSP34
Molecular Weight(MW)
35432 Da
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Tissue Specificity
This CRSP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154~184 amino acids from the center region of human CRSP8.
Western blot analysis of anti-CRSP8 Antibody (Center) in K562 cell line lysates (35ug/lane). CRSP8 (arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.