Application
CRY2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CRY2 antibody detected the CRY2 protein (arrow).| Product Name | CRY2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRY2; KIAA0658; Cryptochrome-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0658 |
|---|---|
| Alternative Names | CRY2 KIAA0658 Cryptochrome-2 |
| Molecular Weight(MW) | 66947 Da |
| Function | Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL |
| Tissue Specificity | Expressed in all tissues examined including fetal brain, fibroblasts, heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Highest levels in heart and skeletal muscle |
| Cellular Localization | Cytoplasm. Nucleus. Note=Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL |
| Entrez Gene | 1408 |
|---|---|
| Nucleotide Accession | NP_001120929.1 NP_066940.2 |
Application
CRY2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CRY2 antibody detected the CRY2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
