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CSF3R Antibody (Center)

Catalog Number:OM230487
OM230487
Discount Price
OM230487-100ul
1~2 Week
100ul
OM230487-50ul
50ul
OM230487-20ul
20ul
1~2 Week
Product Profile
Product Name CSF3R Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias CSF3R; GCSFR; Granulocyte colony-stimulating factor receptor; CD_antigen=CD114; Flags: Precursor
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms GCSFR
Alternative Names CSF3R
GCSFR
Granulocyte colony-stimulating factor receptor
CD_antigen=CD114
Flags: Precursor
Molecular Weight(MW) 92156 Da
Function Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface
Tissue Specificity One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U-937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes Isoform GCSFR-2 is found only in leukemia U-937 cells. Isoform GCSFR-3 is highly expressed in placenta
Cellular Localization Isoform 2: Secreted (Probable).
Database Links
Entrez Gene 1441
Application

Application

Western blot analysis of CSF3R Antibody (Center) in HL-60 cell line lysates (35ug/lane). CSF3R (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human colon carcinoma reacted with CSF3R Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

CSF3R Antibody (Center) FC analysis of ZR-75-1 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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