Application
CTDSPL Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CTDSPL antibody detected the CTDSPL protein (arrow).Application
CTDSPL Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CTDSPL Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTDSPL; C3orf8; NIF1; NIFL; SCP3; YA22; CTD small phosphatase-like protein; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; NIF-like protein; Nuclear LIM interactor-interacting factor 1; Protein YA22; RBSP3; Small C-terminal do |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C3orf8 NIF1 NIFL SCP3 YA22 |
|---|---|
| Alternative Names | CTDSPL C3orf8 NIF1 NIFL SCP3 YA22 CTD small phosphatase-like protein Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3 NIF-like protein Nuclear LIM interactor-interacting factor 1 Protein YA22 RBSP3 Small C-terminal do |
| Molecular Weight(MW) | 31129 Da |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation (By similarity). Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells |
| Tissue Specificity | Expression is restricted to non-neuronal tissues |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 10217 |
|---|---|
| Nucleotide Accession | NP_001008393.1 NP_005799.2 |
Application
CTDSPL Antibody (N-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CTDSPL antibody detected the CTDSPL protein (arrow).
Application
CTDSPL Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
