CYFIP2 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CYFIP2 antibody detected the CYFIP2 protein (arrow).
CYFIP2; KIAA1168; PIR121; Cytoplasmic FMR1-interacting protein 2; p53-inducible protein 121
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
KIAA1168 PIR121
Alternative Names
CYFIP2 KIAA1168 PIR121 Cytoplasmic FMR1-interacting protein 2 p53-inducible protein 121
Molecular Weight(MW)
148399 Da
Function
Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA
Tissue Specificity
Expressed in T-cells. Increased expression is observed in CD4(+) T-lymphocytes from patients with multiple sclerosis (at protein level)
Cellular Localization
Cytoplasm. Cytoplasm, perinuclear region. Cell junction, synapse, synaptosome. Note=Highly expressed in the perinuclear region. Enriched in synaptosomes. Treatment with leptomycin-B triggers translocation to the nucleus
CYFIP2 Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the CYFIP2 antibody detected the CYFIP2 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.