Application
Confocal immunofluorescent analysis of CYP17A1 Antibody (Center) with Hela cell followed by Alexa Fluor搴?488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
Western blot analysis of anti-CYP17A1 Antibody (Center) in K562 cell line lysates (35ug/lane). CYP17A1(arrow) was detected using the purified Pab.| Product Name | CYP17A1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP17A1; CYP17; S17AH; Steroid 17-alpha-hydroxylase/17, 20 lyase; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Steroid 17-alpha-monooxygenase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IFWB |
| IF:1:10~50 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CYP17 S17AH |
|---|---|
| Alternative Names | CYP17A1 CYP17 S17AH Steroid 17-alpha-hydroxylase/17 20 lyase CYPXVII Cytochrome P450 17A1 Cytochrome P450-C17 Steroid 17-alpha-monooxygenase |
| Molecular Weight(MW) | 57371 Da |
| Function | Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty |
| Tissue Specificity | This CYP17A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366~395 amino acids from the Center region of human CYP17A1. |
| Cellular Localization | Membrane (Potential). |
| Entrez Gene | 1586 |
|---|
Application
Confocal immunofluorescent analysis of CYP17A1 Antibody (Center) with Hela cell followed by Alexa Fluor搴?488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
Western blot analysis of anti-CYP17A1 Antibody (Center) in K562 cell line lysates (35ug/lane). CYP17A1(arrow) was detected using the purified Pab.| Application Notes | IF:1:10~50 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
