Application
Western blot analysis of CYP24A1 Antibody (C-term) in mouse spleen tissue lysates (35ug/lane). CYP24A1 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human spleen tissue reacted with DLX2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | CYP24A1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP24A1; CYP24; 1, 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Cytochrome P450 24A1; Cytochrome P450-CC24 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CYP24 |
|---|---|
| Alternative Names | CYP24A1 CYP24 1 25-dihydroxyvitamin D(3) 24-hydroxylase mitochondrial Cytochrome P450 24A1 Cytochrome P450-CC24 |
| Molecular Weight(MW) | 58875 Da |
| Function | Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product |
| Tissue Specificity | This CYP24A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473~502 amino acids from the C-terminal region of human CYP24A1. |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 1591 |
|---|
Application
Western blot analysis of CYP24A1 Antibody (C-term) in mouse spleen tissue lysates (35ug/lane). CYP24A1 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human spleen tissue reacted with DLX2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Data sheet for OM230791