Application
Western blot analysis of anti-CYP26A1 Antibody (Center) in Jurkat cell line lysates (35ug/lane).CYP26A1(arrow) was detected using the purified Pab (1:60dilution).| Product Name | CYP26A1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP26A1; CYP26; P450RAI1; Cytochrome P450 26A1; Cytochrome P450 retinoic acid-inactivating 1; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CYP26 P450RAI1 |
|---|---|
| Alternative Names | CYP26A1 CYP26 P450RAI1 Cytochrome P450 26A1 Cytochrome P450 retinoic acid-inactivating 1 Retinoic acid 4-hydroxylase Retinoic acid-metabolizing cytochrome |
| Molecular Weight(MW) | 56199 Da |
| Function | Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA |
| Tissue Specificity | Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain |
| Cellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein |
Application
Western blot analysis of anti-CYP26A1 Antibody (Center) in Jurkat cell line lysates (35ug/lane).CYP26A1(arrow) was detected using the purified Pab (1:60dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
