Application
Western blot analysis of anti-CYP2C8 Antibody (N-term) in T47D cell line lysates (35ug/lane). CYP2C8(arrow) was detected using the purified Pab.| Product Name | CYP2C8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP2C8; Cytochrome P450 2C8; CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CYP2C8 Cytochrome P450 2C8 CYPIIC8 Cytochrome P450 IIC2 Cytochrome P450 MP-12 Cytochrome P450 MP-20 Cytochrome P450 form 1 S-mephenytoin 4-hydroxylase |
|---|---|
| Molecular Weight(MW) | 55825 Da |
| Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti- cancer drug paclitaxel (taxol) |
| Tissue Specificity | This CYP2C8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82~112 amino acids from the N-terminal region of human CYP2C8. |
| Cellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein |
| Entrez Gene | 1558 |
|---|
Application
Western blot analysis of anti-CYP2C8 Antibody (N-term) in T47D cell line lysates (35ug/lane). CYP2C8(arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
