Application
Western blot analysis of CYP2D6 Antibody (N-term) in K562, Jurkat, T47D cell line lysates (35ug/lane). CYP2D6 (arrow) was detected using the purified Pab.Application
Confocal immunofluorescent analysis of CYP2D6 Antibody (N-term)(Cat#AP7882a) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).Application
CYP2D6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP2D6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
CYP2D6 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CYP2D6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CYP2D6; CYP2DL1; Cytochrome P450 2D6; CYPIID6; Cytochrome P450-DB1; Debrisoquine 4-hydroxylase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIFIHCFC |
| WB:1:50~100 IF |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CYP2DL1 |
|---|---|
| Alternative Names | CYP2D6 CYP2DL1 Cytochrome P450 2D6 CYPIID6 Cytochrome P450-DB1 Debrisoquine 4-hydroxylase |
| Molecular Weight(MW) | 55769 Da |
| Function | Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants |
| Tissue Specificity | This CYP2D6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80~110 amino acids from the N-terminal region of human CYP2D6. |
| Cellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein |
| Entrez Gene | 1565 |
|---|
Application
Western blot analysis of CYP2D6 Antibody (N-term) in K562, Jurkat, T47D cell line lysates (35ug/lane). CYP2D6 (arrow) was detected using the purified Pab.
Application
Confocal immunofluorescent analysis of CYP2D6 Antibody (N-term)(Cat#AP7882a) with MDA-MB435 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Application
CYP2D6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP2D6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
CYP2D6 Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:50~100 IF |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
