Catalyzes leukotriene B4 omega-hydroxylation and arachidonic acid omega-hydroxylation but with an activity much lower than that of CYP4F2. Catalyzes the hydroxylation of the antihistamine ebastine
Tissue Specificity
Expressed in small intestine, liver, colon and heart
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Microsome membrane; Multi-pass membrane protein (By similarity)
Western blot analysis of anti-CYP4F12 Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). CYP4F12(arrow) was detected using the purified Pab.
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.