Application
DAD1 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the DAD1 antibody detected the DAD1 protein (arrow).| Product Name | DAD1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DAD1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Defender against cell death 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DAD1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 Defender against cell death 1 |
|---|---|
| Molecular Weight(MW) | 12497 Da |
| Function | Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis (By similarity) |
| Tissue Specificity | This DAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the C-terminal region of human DAD1. |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity) |
| Entrez Gene | 1603 |
|---|---|
| Nucleotide Accession | NP_001335.1 |
Application
DAD1 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the DAD1 antibody detected the DAD1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
