Application
DARC Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DARC antibody detected the DARC protein (arrow).| Product Name | DARC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DARC; FY; GPD; Duffy antigen/chemokine receptor; Fy glycoprotein; Glycoprotein D; Plasmodium vivax receptor; CD_antigen=CD234 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FY GPD |
|---|---|
| Alternative Names | DARC FY GPD Duffy antigen/chemokine receptor Fy glycoprotein Glycoprotein D Plasmodium vivax receptor CD_antigen=CD234 |
| Molecular Weight(MW) | 35553 Da |
| Function | Non-specific receptor for many chemokines such as IL-8, GRO, RANTES, MCP-1 and TARC. It is also the receptor for the human malaria parasites Plasmodium vivax and Plasmodium knowlesi |
| Tissue Specificity | Found in adult kidney, adult spleen, bone marrow and fetal liver. In particular, it is expressed along postcapillary venules throughout the body, except in the adult liver. Erythroid cells and postcapillary venule endothelium are the principle tissues expressing duffy. Fy(-A-B) individuals do not express duffy in the bone marrow, however they do, in postcapillary venule endothelium |
| Cellular Localization | Membrane; Multi-pass membrane protein. |
| Entrez Gene | 2532 |
|---|---|
| Nucleotide Accession | NP_002027.2 |
Application
DARC Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DARC antibody detected the DARC protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
