Application
DBNL Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DBNL antibody detected the DBNL protein (arrow).| Product Name | DBNL Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DBNL; CMAP; SH3P7; Drebrin-like protein; Cervical SH3P7; Cervical mucin-associated protein; Drebrin-F; HPK1-interacting protein of 55 kDa; SH3 domain-containing protein 7 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CMAP SH3P7 |
|---|---|
| Alternative Names | DBNL CMAP SH3P7 Drebrin-like protein Cervical SH3P7 Cervical mucin-associated protein Drebrin-F HPK1-interacting protein of 55 kDa SH3 domain-containing protein 7 |
| Molecular Weight(MW) | 48207 Da |
| Function | Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin |
| Tissue Specificity | This DBNL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human DBNL. |
| Cellular Localization | Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Note=Cortical cytoskeleton. Associates with lamellipodial actin |
| Entrez Gene | 28988 |
|---|---|
| Nucleotide Accession | NP_001014436.1 NP_001116428.1 |
Application
DBNL Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DBNL antibody detected the DBNL protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
