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DCD Antibody (C-term)

Catalog Number:OM231030
OM231030
Discount Price
OM231030-100ul
1~2 Week
100ul
OM231030-50ul
50ul
OM231030-20ul
20ul
1~2 Week
Product Profile
Product Name DCD Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias DCD; AIDD; DSEP; Dermcidin; Preproteolysin; Survival-promoting peptide; DCD-1
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:50~100 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms AIDD
DSEP
Alternative Names DCD
AIDD
DSEP
Dermcidin
Preproteolysin
Survival-promoting peptide
DCD-1
Molecular Weight(MW) 11284 Da
Function DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity
Tissue Specificity Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml
Cellular Localization Secreted.
Database Links
Entrez Gene 117159
Application

Application

Western blot analysis of DCD antibody (C-term) in T47D cell line lysates (35ug/lane). DCD (arrow) was detected using the purified Pab.

Application

DCD Antibody (C-term) (RB18706) IHC analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCD Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

DCD Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:50~100 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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