Application
Western blot analysis of DCLRE1A Antibody (Center)（) in WiDr cell line lysates (35ug/lane). DCLRE1A (arrow) was detected using the purified Pab.| Product Name | DCLRE1A Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DCLRE1A; KIAA0086; SNM1; SNM1A; DNA cross-link repair 1A protein; SNM1 homolog A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0086 SNM1 SNM1A |
|---|---|
| Alternative Names | DCLRE1A KIAA0086 SNM1 SNM1A DNA cross-link repair 1A protein SNM1 homolog A |
| Molecular Weight(MW) | 116400 Da |
| Function | May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, pancreas, placenta and skeletal muscle |
| Cellular Localization | Nucleus. Note=In some cells it may be found in typically 1 or 2 discrete nuclear aggregates of unknown function which also contain TP53BP1. Also found in multiple discrete nuclear foci which increase in number following treatment with ionizing radiation or interstrand cross-linking agents. These foci overlap with those formed by the MRN complex (composed of MRE11A, RAD50 and NBN) and BRCA1 |
| Entrez Gene | 9937 |
|---|
Application
Western blot analysis of DCLRE1A Antibody (Center)（) in WiDr cell line lysates (35ug/lane). DCLRE1A (arrow) was detected using the purified Pab.| Application Notes | WB:1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
