Application
Western blot analysis of Dcr-1 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). Dcr-1 (arrow) was detected using the purified Pab.| Product Name | Dcr-1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | dcr-1; Endoribonuclease dcr-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | dcr-1 Endoribonuclease dcr-1 |
|---|---|
| Molecular Weight(MW) | 218423 Da |
| Function | Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing |
| Tissue Specificity | This Dcr-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of C. elegans Dcr-1. |
| Entrez Gene | 176138 |
|---|
Application
Western blot analysis of Dcr-1 Antibody (C-term) in MDA-MB231 cell line lysates (35ug/lane). Dcr-1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
