Application
DEPDC1 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the DEPDC1 antibody detected the DEPDC1 protein (arrow).Application
DEPDC1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DEPDC1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DEPDC1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DEPDC1; DEPDC1A; DEP domain-containing protein 1A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DEPDC1A |
|---|---|
| Alternative Names | DEPDC1 DEPDC1A DEP domain-containing protein 1A |
| Molecular Weight(MW) | 92960 Da |
| Function | May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells |
| Tissue Specificity | Expressed in testis. Up-regulated in bladder cancer cells (at protein level) |
| Cellular Localization | Nucleus. Note=Co-localizes with ZNF224 at the nucleus |
| Entrez Gene | 55635 |
|---|---|
| Nucleotide Accession | NP_001107592.1 NP_060249.2 |
Application
DEPDC1 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the DEPDC1 antibody detected the DEPDC1 protein (arrow).
Application
DEPDC1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DEPDC1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
