Application
DENND2A Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the DENND2A antibody detected the DENND2A protein (arrow).Application
DENND2A antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DENND2A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DENND2A Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DENND2A; KIAA1277; DENN domain-containing protein 2A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1277 |
|---|---|
| Alternative Names | DENND2A KIAA1277 DENN domain-containing protein 2A |
| Molecular Weight(MW) | 113853 Da |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. May play a role in late endosomes back to trans-Golgi network/TGN transport |
| Tissue Specificity | This DENND2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-614 amino acids from the Central region of human DENND2A. |
| Cellular Localization | Cytoplasm, cytoskeleton. Note=Associated with actin filaments |
| Entrez Gene | 27147 |
|---|---|
| Nucleotide Accession | NP_056504.3 |
Application
DENND2A Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the DENND2A antibody detected the DENND2A protein (arrow).
Application
DENND2A antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DENND2A antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
