Application
DENND5B Antibody (C-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the DENND5B antibody detected DENND5B protein (arrow).Application
DENND5B antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DENND5B antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DENND5B Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DENND5B; DENN domain-containing protein 5B; Rab6IP1-like protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DENND5B DENN domain-containing protein 5B Rab6IP1-like protein |
|---|---|
| Molecular Weight(MW) | 145020 Da |
| Function | Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form |
| Tissue Specificity | This DENND5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073-1102 amino acids from the C-terminal region of human DENND5B. |
| Cellular Localization | Membrane; Single-pass membrane protein (Potential) |
| Entrez Gene | 160518 |
|---|---|
| Nucleotide Accession | NP_659410.3 |
Application
DENND5B Antibody (C-term) western blot analysis in mouse liver tissue lysates (15ug/lane).This demonstrates the DENND5B antibody detected DENND5B protein (arrow).
Application
DENND5B antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DENND5B antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
