Application
DFNB31 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DFNB31 antibody detected the DFNB31 protein (arrow).Application
DFNB31 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DFNB31 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DFNB31 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WHRN; DFNB31; KIAA1526; Whirlin; Autosomal recessive deafness type 31 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1526 WHRN |
|---|---|
| Alternative Names | WHRN DFNB31 KIAA1526 Whirlin Autosomal recessive deafness type 31 protein |
| Molecular Weight(MW) | 96586 Da |
| Function | Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear (By similarity) |
| Tissue Specificity | This DFNB31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-413 amino acids from the Central region of human DFNB31. |
| Cellular Localization | Cytoplasm (By similarity). Cell projection, stereocilium (By similarity). Cell projection, growth cone (By similarity). Note=Detected at the level of stereocilia in inner outer hair cells of the cochlea and vestibule. Co-localizes with the growing ends of actin filaments (By similarity). Colocalizes with MPP1 in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) |
| Entrez Gene | 25861 |
|---|---|
| Nucleotide Accession | NP_056219.3 NP_001077354.2 |
Application
DFNB31 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DFNB31 antibody detected the DFNB31 protein (arrow).
Application
DFNB31 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DFNB31 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
