Application
Western blot analysis of DGAT2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). DGAT2 (arrow) was detected using the purified Pab.| Product Name | DGAT2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DGAT2; Diacylglycerol O-acyltransferase 2; Acyl-CoA retinol O-fatty-acyltransferase; Diglyceride acyltransferase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DGAT2 Diacylglycerol O-acyltransferase 2 Acyl-CoA retinol O-fatty-acyltransferase Diglyceride acyltransferase 2 |
|---|---|
| Molecular Weight(MW) | 43831 Da |
| Function | Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT) |
| Tissue Specificity | Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. Lipid droplet (By similarity) |
| Entrez Gene | 84649 |
|---|
Application
Western blot analysis of DGAT2 Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). DGAT2 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
