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DGKZ Antibody (C-term)

Catalog Number:OM231244
OM231244
Discount Price
OM231244-100ul
1~2 Week
100ul
OM231244-50ul
50ul
OM231244-20ul
20ul
1~2 Week
Product Profile
Product Name DGKZ Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias DGKZ; DAGK6; Diacylglycerol kinase zeta; Diglyceride kinase zeta
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms DAGK6
Alternative Names DGKZ
DAGK6
Diacylglycerol kinase zeta
Diglyceride kinase zeta
Molecular Weight(MW) 124128 Da
Function Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity
Tissue Specificity Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle
Cellular Localization Cytoplasm. Nucleus. Cell membrane.
Database Links
Entrez Gene 8525
Application

Application

DGKZ Antibody (D1004) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the DGKZ antibody detected the DGKZ protein (arrow).

Application

Western blot analysis of DGKZ (arrow) using DGKZ Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DGKZ gene (Lane 2) (Origene Technologies).

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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