Application
DHFRL1 Antibody (Center) western blot analysis in 293,Hela,K562 cell line lysates (35ug/lane).This demonstrates the DHFRL1 antibody detected the DHFRL1 protein (arrow).Application
DHFRL1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DHFRL1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DHFRL1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DHFRL1; DHFRP4; Dihydrofolate reductase, mitochondrial; Dihydrofolate reductase-like protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DHFRP4 |
|---|---|
| Alternative Names | DHFRL1 DHFRP4 Dihydrofolate reductase mitochondrial Dihydrofolate reductase-like protein 1 |
| Molecular Weight(MW) | 21620 Da |
| Function | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR |
| Tissue Specificity | Expressed in numerous cell lines. |
| Cellular Localization | Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane |
| Entrez Gene | 200895 |
|---|---|
| Nucleotide Accession | NP_789785.1 |
Application
DHFRL1 Antibody (Center) western blot analysis in 293,Hela,K562 cell line lysates (35ug/lane).This demonstrates the DHFRL1 antibody detected the DHFRL1 protein (arrow).
Application
DHFRL1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DHFRL1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
