Application
DHRS4 Antibody (Center) western blot analysis in MCF-7,Jurkat,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the DHRS4 antibody detected the DHRS4 protein (arrow).| Product Name | DHRS4 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DHRS4; Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; NADPH-dependent retinol dehydrogenase/reductase; Peroxisomal short-chain alcohol dehydrogenase; SCAD-SRL; Short-chain dehydrogenase/reductase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DHRS4 Dehydrogenase/reductase SDR family member 4 NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase NADPH-dependent retinol dehydrogenase/reductase Peroxisomal short-chain alcohol dehydrogenase SCAD-SRL Short-chain dehydrogenase/reductase |
|---|---|
| Molecular Weight(MW) | 29537 Da |
| Function | Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co- factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity) |
| Tissue Specificity | Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues |
| Cellular Localization | Peroxisome. Note=Isoform 1 is peroxisomal, while isoform 4 is not |
| Entrez Gene | 10901 |
|---|---|
| Nucleotide Accession | NP_066284.2 |
Application
DHRS4 Antibody (Center) western blot analysis in MCF-7,Jurkat,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the DHRS4 antibody detected the DHRS4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
