Application
DHRS9 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the DHRS9 antibody detected the DHRS9 protein (arrow).Application
DHRS9 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DHRS9 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DHRS9 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DHRS9; Dehydrogenase/reductase SDR family member 9; 3-alpha hydroxysteroid dehydrogenase; NADP-dependent retinol dehydrogenase/reductase; RDH-E2; RDHL; Short-chain dehydrogenase/reductase retSDR8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DHRS9 Dehydrogenase/reductase SDR family member 9 3-alpha hydroxysteroid dehydrogenase NADP-dependent retinol dehydrogenase/reductase RDH-E2 RDHL Short-chain dehydrogenase/reductase retSDR8 |
|---|---|
| Molecular Weight(MW) | 35227 Da |
| Function | 3-alpha-hydroxysteroid dehydrogenase that converts 3- alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH |
| Tissue Specificity | Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node |
| Cellular Localization | Microsome membrane. Endoplasmic reticulum membrane (Potential). Note=Associated with microsomal membranes |
| Entrez Gene | 10170 |
|---|---|
| Nucleotide Accession | NP_954674.1 NP_001135742.1 NP_001135743.1 NP_005762.2 |
Application
DHRS9 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the DHRS9 antibody detected the DHRS9 protein (arrow).
Application
DHRS9 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DHRS9 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
