Application
DI3L1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).Application
DI3L1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DI3L1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DI3L1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DIS3L; DIS3L1; KIAA1955; DIS3-like exonuclease 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DIS3L1 KIAA1955 |
|---|---|
| Alternative Names | DIS3L DIS3L1 KIAA1955 DIS3-like exonuclease 1 |
| Molecular Weight(MW) | 120787 Da |
| Function | Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA |
| Tissue Specificity | This DI3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-232 amino acids from the N-terminal region of human DI3L1. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 115752 |
|---|---|
| Nucleotide Accession | NP_001137160.1 |
Application
DI3L1 Antibody (N-term) western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the DI3L1 antibody detected DI3L1 protein (arrow).
Application
DI3L1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DI3L1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
