Application
Western blot analysis of DIO1 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). DIO1 (arrow) was detected using the purified Pab.| Product Name | DIO1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DIO1; ITDI1; TXDI1; Type I iodothyronine deiodinase; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ITDI1 TXDI1 |
|---|---|
| Alternative Names | DIO1 ITDI1 TXDI1 Type I iodothyronine deiodinase 5DI DIOI Type 1 DI Type-I 5'-deiodinase |
| Molecular Weight(MW) | 28924 Da |
| Function | Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney |
| Tissue Specificity | This DIO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36~66 amino acids from the N-terminal region of human DIO1. |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity) |
| Entrez Gene | 1733 |
|---|
Application
Western blot analysis of DIO1 Antibody (N-term) in HepG2 cell line lysates (35ug/lane). DIO1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
