Application
DND1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow).| Product Name | DND1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DND1; RBMS4; Dead end protein homolog 1; RNA-binding motif, single-stranded-interacting protein 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | RBMS4 |
|---|---|
| Alternative Names | DND1 RBMS4 Dead end protein homolog 1 RNA-binding motif single-stranded-interacting protein 4 |
| Molecular Weight(MW) | 38687 Da |
| Function | RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression Relieves miRNA repression in germline cells (By similarity) Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity) |
| Tissue Specificity | This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human DND1. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3 (By similarity) |
| Entrez Gene | 373863 |
|---|---|
| Nucleotide Accession | NP_919225.1 |
Application
DND1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
