Application
DOK3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DOK3 antibody detected the DOK3 protein (arrow).Application
DOK3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DOK3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DOK3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DOK3; Docking protein 3; Downstream of tyrosine kinase 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DOK3 Docking protein 3 Downstream of tyrosine kinase 3 |
|---|---|
| Molecular Weight(MW) | 53288 Da |
| Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity) |
| Tissue Specificity | Expressed in spleen. |
| Cellular Localization | Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity) |
| Entrez Gene | 79930 |
|---|---|
| Nucleotide Accession | NP_079148.2 |
Application
DOK3 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DOK3 antibody detected the DOK3 protein (arrow).
Application
DOK3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DOK3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
