Application
DR1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DR1 antibody detected the DR1 protein (arrow).Application
DR1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the DR1 antibody detected the DR1 protein (arrow).| Product Name | DR1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DR1; Protein Dr1; Down-regulator of transcription 1; Negative cofactor 2-beta; TATA-binding protein-associated phosphoprotein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DR1 Protein Dr1 Down-regulator of transcription 1 Negative cofactor 2-beta TATA-binding protein-associated phosphoprotein |
|---|---|
| Molecular Weight(MW) | 19444 Da |
| Function | The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 |
| Tissue Specificity | This DR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-112 amino acids from the Central region of human DR1. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 1810 |
|---|---|
| Nucleotide Accession | NP_001929.1 |
Application
DR1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DR1 antibody detected the DR1 protein (arrow).
Application
DR1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the DR1 antibody detected the DR1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
