Application
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Western blot analysis of DRAGON (RGMB) Antibody (C-term) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab (1:60 dilution).| Product Name | DRAGON (RGMB) Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGMB; RGM domain family member B; DRG11-responsive axonal guidance and outgrowth of neurite |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:10~50 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | RGMB RGM domain family member B DRG11-responsive axonal guidance and outgrowth of neurite |
|---|---|
| Molecular Weight(MW) | 47547 Da |
| Function | Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity) Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth |
| Tissue Specificity | This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387~416 amino acids from the C-terminal region of human DRAGON. |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor (By similarity). Membrane raft (By similarity) |
| Entrez Gene | 285704 |
|---|
Application
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Western blot analysis of DRAGON (RGMB) Antibody (C-term) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | IHC:1:10~50 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
