Application
DTNA Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DTNA antibody detected the DTNA protein (arrow).Application
DTNA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DTNA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Confocal immunofluorescent analysis of DTNA Antibody (C-term) (Cat#AP12573b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | DTNA Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DTNA; DRP3; Dystrobrevin alpha; Alpha-dystrobrevin; Dystrophin-related protein 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DRP3 |
|---|---|
| Alternative Names | DTNA DRP3 Dystrobrevin alpha Alpha-dystrobrevin Dystrophin-related protein 3 |
| Molecular Weight(MW) | 83901 Da |
| Function | May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors |
| Tissue Specificity | Highly expressed in brain, skeletal and cardiac muscles, and expressed at lower levels in lung, liver and pancreas. Isoform 2 is not expressed in cardiac muscle. Isoform 7 and isoform 8 are only expressed in muscle |
| Cellular Localization | Cytoplasm. Cell junction, synapse. Cell membrane (By similarity). Note=In peripheral nerves, co-localizes with MAGEE1 in the Schwann cell membrane (By similarity) |
| Entrez Gene | 1837 |
|---|---|
| Nucleotide Accession | NP_116760.2 NP_001383.2 |
Application
DTNA Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the DTNA antibody detected the DTNA protein (arrow).
Application
DTNA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DTNA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Confocal immunofluorescent analysis of DTNA Antibody (C-term) (Cat#AP12573b) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
