Application
DUOX2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow).Application
DUOX2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | DUOX2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DUOX2; LNOX2; THOX2; Dual oxidase 2; Large NOX 2; Long NOX 2; NADH/NADPH thyroid oxidase p138-tox; NADPH oxidase/peroxidase DUOX2; NADPH thyroid oxidase 2; Thyroid oxidase 2; p138 thyroid oxidase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LNOX2 THOX2 |
|---|---|
| Alternative Names | DUOX2 LNOX2 THOX2 Dual oxidase 2 Large NOX 2 Long NOX 2 NADH/NADPH thyroid oxidase p138-tox NADPH oxidase/peroxidase DUOX2 NADPH thyroid oxidase 2 Thyroid oxidase 2 p138 thyroid oxidase |
| Molecular Weight(MW) | 175364 Da |
| Function | Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain |
| Tissue Specificity | Expressed in colon, small intestine, duodenum and tracheal surface epithelial cells (at protein level) Expressed in thyrocytes. Also detected in kidney, liver, lung, pancreas, prostate, salivary glands, rectum and testis |
| Cellular Localization | Apical cell membrane; Multi-pass membrane protein. Note=Localizes to the apical membrane of epithelial cells |
Application
DUOX2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow).
Application
DUOX2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
