Application
Western blot analysis of hDUSP1-S344 in HepG2 cell line lysates (35ug/lane). DUSP1 (arrow) was detected using the purified Pab.Application
Confocal immunofluorescent analysis of DUSP1 Antibody (C-term)(Cat#AP8470b) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | DUSP1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; Mitogen-activated protein kinase phosphatase 1; Protein-tyrosine phosphatase CL100 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:50~100 IF |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CL100 MKP1 PTPN10 VH1 |
|---|---|
| Alternative Names | DUSP1 CL100 MKP1 PTPN10 VH1 Dual specificity protein phosphatase 1 Dual specificity protein phosphatase hVH1 Mitogen-activated protein kinase phosphatase 1 Protein-tyrosine phosphatase CL100 |
| Molecular Weight(MW) | 39298 Da |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle (By similarity) |
| Tissue Specificity | Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 1843 |
|---|
Application
Western blot analysis of hDUSP1-S344 in HepG2 cell line lysates (35ug/lane). DUSP1 (arrow) was detected using the purified Pab.
Application
Confocal immunofluorescent analysis of DUSP1 Antibody (C-term)(Cat#AP8470b) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | WB:1:50~100 IF |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
