Western blot analysis of DUSP23 (arrow) using rabbit polyclonal DUSP23 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DUSP23 gene (Lane 2) (Origene Technologies).
DUSP23; LDP3; VHZ; Dual specificity protein phosphatase 23; Low molecular mass dual specificity phosphatase 3; VH1-like phosphatase Z
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:50~100
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
LDP3 VHZ
Alternative Names
DUSP23 LDP3 VHZ Dual specificity protein phosphatase 23 Low molecular mass dual specificity phosphatase 3 VH1-like phosphatase Z
Molecular Weight(MW)
16588 Da
Function
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14)
Tissue Specificity
Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach
Cellular Localization
Cytoplasm, cytosol. Nucleus. Note=Mainly cytosolic. Also nuclear
Western blot analysis of DUSP23 (arrow) using rabbit polyclonal DUSP23 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DUSP23 gene (Lane 2) (Origene Technologies).
Application Notes
WB:1:50~100
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.