Application
DUT Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the DUT antibody detected the DUT protein (arrow).Application
DUT Antibody (C-term) (AP14203b)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DUT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DUT Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DUT; Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; dUTP pyrophosphatase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DUT Deoxyuridine 5'-triphosphate nucleotidohydrolase mitochondrial dUTP pyrophosphatase |
|---|---|
| Molecular Weight(MW) | 26563 Da |
| Function | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA |
| Tissue Specificity | Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level) |
| Cellular Localization | Isoform 2: Nucleus. |
| Entrez Gene | 1854 |
|---|---|
| Nucleotide Accession | NP_001939.1 NP_001020419.1 NP_001020420.1 |
Application
DUT Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the DUT antibody detected the DUT protein (arrow).
Application
DUT Antibody (C-term) (AP14203b)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DUT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
