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DYNC1I1 Antibody (C-term)

Catalog Number:OM231725
OM231725
Discount Price
OM231725-100ul
1~2 Week
100ul
OM231725-50ul
50ul
OM231725-20ul
20ul
1~2 Week
Product Profile
Product Name DYNC1I1 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias DYNC1I1; DNCI1; DNCIC1; Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; Dynein intermediate chain 1, cytosolic
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFC
WB:1:100~500 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms DNCI1
DNCIC1
Alternative Names DYNC1I1
DNCI1
DNCIC1
Cytoplasmic dynein 1 intermediate chain 1
Cytoplasmic dynein intermediate chain 1
Dynein intermediate chain 1
cytosolic
Molecular Weight(MW) 72955 Da
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores
Tissue Specificity This DYNC1I1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 612~642 amino acids from the C-terminal region of human DYNC1I1.
Cellular Localization Cytoplasm (By similarity). Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole
Database Links
Entrez Gene 1780
Application

Application

Western blot analysis of DYNC1I1 Antibody (C-term) in mouse cerebellum and mouse brain tissue lysates (35ug/lane).DYNC1I1 (arrow) was detected using the purified Pab.

Application

DYNC1I1 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

Western blot analysis of DYNC1I1 (arrow) using rabbit polyclonal DYNC1I1 Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DYNC1I1 gene.
Application Notes WB:1:100~500 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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