Application
DYRK1B Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DYRK1B antibody detected the DYRK1B protein (arrow).| Product Name | DYRK1B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DYRK1B; MIRK; Dual specificity tyrosine-phosphorylation-regulated kinase 1B; Minibrain-related kinase; Mirk protein kinase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MIRK |
|---|---|
| Alternative Names | DYRK1B MIRK Dual specificity tyrosine-phosphorylation-regulated kinase 1B Minibrain-related kinase Mirk protein kinase |
| Molecular Weight(MW) | 69198 Da |
| Function | Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments |
| Tissue Specificity | Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines |
| Cellular Localization | Nucleus. |
| Entrez Gene | 9149 |
|---|---|
| Nucleotide Accession | NP_004705.1 NP_006474.1 |
Application
DYRK1B Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DYRK1B antibody detected the DYRK1B protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
