Application
EFNA2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the EFNA2 antibody detected the EFNA2 protein (arrow).| Product Name | EFNA2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EPLG6, LERK6 |
|---|---|
| Alternative Names | EFNA2 EPLG6 LERK6 Ephrin-A2 EPH-related receptor tyrosine kinase ligand 6 HEK7 ligand |
| Molecular Weight(MW) | 23878 Da |
| Function | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity) |
| Tissue Specificity | This EFNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human EFNA2. |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor (Potential) |
| Entrez Gene | 1943 |
|---|---|
| Nucleotide Accession | NP_001396.2 |
Application
EFNA2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the EFNA2 antibody detected the EFNA2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
