Application
EIF3L Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the EIF3L antibody detected the EIF3L protein (arrow).| Product Name | EIF3L Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EIF3EIP, EIF3S6IP |
|---|---|
| Alternative Names | EIF3L EIF3EIP EIF3S6IP Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit 6-interacting protein Eukaryotic translation initiation factor 3 subunit E-interacting protein |
| Molecular Weight(MW) | 66727 Da |
| Function | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation |
| Tissue Specificity | This EIF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human EIF3L. |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 51386 |
|---|---|
| Nucleotide Accession | NP_057175.1 |
Application
EIF3L Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the EIF3L antibody detected the EIF3L protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
