Application
EIF5A2 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the EIF5A2 antibody detected the EIF5A2 protein (arrow).Application
EIF5A2 Antibody (C-term) (AP14052b)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF5A2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | EIF5A2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EIF5A2; Eukaryotic translation initiation factor 5A-2; Eukaryotic initiation factor 5A isoform 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | EIF5A2 Eukaryotic translation initiation factor 5A-2 Eukaryotic initiation factor 5A isoform 2 |
|---|---|
| Molecular Weight(MW) | 16793 Da |
| Function | mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity) |
| Tissue Specificity | Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis Overexpressed in some cancer cells |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Nucleus, nuclear pore complex (By similarity). Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions (By similarity) |
| Entrez Gene | 56648 |
|---|---|
| Nucleotide Accession | NP_065123.1 |
Application
EIF5A2 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the EIF5A2 antibody detected the EIF5A2 protein (arrow).
Application
EIF5A2 Antibody (C-term) (AP14052b)immunohistochemistry analysis in formalin fixed and paraffin embedded human ovarian carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF5A2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
