Application
ELAVL1 antibody (Cat. #AM1899a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELAVL1 antibody detected the ELAVL1 protein (arrow).| Product Name | ELAVL1 antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 224CT6.5.3 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~16000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HUR |
|---|---|
| Alternative Names | ELAVL1 HUR ELAV-like protein 1 Hu-antigen R |
| Molecular Weight(MW) | 36092 Da |
| Function | Involved in 3'-UTR ARE-mediated MYC stabilization. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm. Nucleus. Note=Translocates into the cytoplasm following phosphorylation by MAPKAPK2 |
| Entrez Gene | 1994 |
|---|---|
| Nucleotide Accession | NP_001410.2 |
Application
ELAVL1 antibody (Cat. #AM1899a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELAVL1 antibody detected the ELAVL1 protein (arrow).| Application Notes | WB:1:500~16000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
