Application
ELFN1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ELFN1 antibody detected the ELFN1 protein (arrow).| Product Name | ELFN1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ELFN1; PPP1R28; Protein phosphatase 1 regulatory subunit 28; Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PPP1R28 |
|---|---|
| Alternative Names | ELFN1 PPP1R28 Protein phosphatase 1 regulatory subunit 28 Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1 |
| Molecular Weight(MW) | 88057 Da |
| Function | Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes |
| Tissue Specificity | This ELFN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 765-792 amino acids selected from the C-terminal region of human ELFN1. |
| Cellular Localization | Membrane; Single-pass type I membrane protein (Potential). Cell projection, dendrite (By similarity) Note=Localizes to excitatory synapses onto somatostatin (Sst)- containing oriens-lacunosum moleculare (O-LM) interneurons (By similarity) |
Application
ELFN1 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ELFN1 antibody detected the ELFN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
