ELOVL4 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ELOVL4 antibody detected the ELOVL4 protein (arrow).
ELOVL4; Elongation of very long chain fatty acids protein 4; 3-keto acyl-CoA synthase ELOVL4; ELOVL fatty acid elongase 4
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
ELOVL4 Elongation of very long chain fatty acids protein 4 3-keto acyl-CoA synthase ELOVL4 ELOVL fatty acid elongase 4
Molecular Weight(MW)
36829 Da
Function
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor- specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development
Tissue Specificity
Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no expression in heart, lung, liver, or leukocates
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein
ELOVL4 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ELOVL4 antibody detected the ELOVL4 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.