Application
ELMO2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELMO2 antibody detected the ELMO2 protein (arrow).Application
ELMO2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELMO2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
ELMO2 Antibody (Center) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Product Name | ELMO2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ELMO2; CED12A; KIAA1834; Engulfment and cell motility protein 2; Protein ced-12 homolog A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CED12A KIAA1834 |
|---|---|
| Alternative Names | ELMO2 CED12A KIAA1834 Engulfment and cell motility protein 2 Protein ced-12 homolog A |
| Molecular Weight(MW) | 82615 Da |
| Function | Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 |
| Tissue Specificity | Widely expressed, with a higher expression in skeletal muscle, kidney and placenta |
| Cellular Localization | Cytoplasm. Cytoplasm, cytosol. Membrane. |
| Entrez Gene | 63916 |
|---|---|
| Nucleotide Accession | NP_877496.1 NP_573403.1 |
Application
ELMO2 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ELMO2 antibody detected the ELMO2 protein (arrow).
Application
ELMO2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ELMO2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
ELMO2 Antibody (Center) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
